Anisotropy of transcallosal motor fibres indicates functional impairment in children with periventricular leukomalacia

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Anisotropy of transcallosal motor fibres indicates functional impairment in children with periventricular leukomalacia.

AIM In children with bilateral spastic cerebral palsy (CP), periventricular leukomalacia (PVL) is commonly identified on magnetic resonance imaging. We characterized this white matter condition by examining callosal microstructure, interhemispheric inhibitory competence (IIC), and mirror movements. METHOD We examined seven children (age range 11y 9mo-17y 9mo, median age 15y 10mo, four females...

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Anisotropy of transcallosal motor fibers indicates functional impairment in children with periventricular leukomalacia INGA KOERTE1,2, PAULA PELAVIN2, BERIT KIRMESS3, TERESA FUCHS3, STEFFEN BERWECK3, RUEDIGER PAUL LAUBENDER4, INGO BORGGRAEFE3, SEBASTIAN SCHROEDER3, ADRIAN DANEK5, CLAUDIA RUMMENY1, MAXIMILIAN REISER1, MAREK

Aim—In children with bilateral spastic cerebral palsy (CP), periventricular leukomalacia (PVL) is commonly identified on magnetic resonance imaging. We characterized this white matter condition by examining callosal microstructure, interhemispheric inhibitory competence (IIC), and mirror movements. Method—We examined 7 children (age range 11y 9mo–17y 9mo, median age 15y 10mo, 4 females) with bi...

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Pontine hypoplasia in children with periventricular leukomalacia.

BACKGROUND AND PURPOSE The brain stem in patients with periventricular leukomalacia (PVL) appears smaller than normal on MR imaging, but few reports have described this feature, and the number of patients has been relatively small. The present study was conducted to examine the hypothesis that the pons in patients with PVL is smaller than normal. MATERIALS AND METHODS Using MR imaging, we exa...

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Neurodevelopmental outcome in children with periventricular leukomalacia.

The purpose of this study was to question the correlation of different grades of periventricular leukomalacia (PVL) and subsequent neurodevelopmental outcome. In a prospective study we followed 52 preterm infants. Infants were divided into three groups according to their cranial ultrasound findings of PVL (De Vries classification). Seventeen children had PVL 1, 20 children had PVL 2, and 15 chi...

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Factors associated with epilepsy in children with periventricular leukomalacia.

Children with cerebral palsy associated with periventricular leukomalacia frequently develop unprovoked epileptic seizures. This article reports an analysis of risk factors for epilepsy in children with radiologically confirmed periventricular leukomalacia. This cohort was screened for epilepsy and for an array of clinical and demographic factors. Of 154 subjects with radiologically confirmed p...

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ژورنال

عنوان ژورنال: Developmental Medicine & Child Neurology

سال: 2010

ISSN: 0012-1622

DOI: 10.1111/j.1469-8749.2010.03840.x